MolNFT v1 · #341745 · protein
AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 4 (P49799)
P49799: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 4 (P49799)”. 1 pocket (best druggability 0.33). MolNFT v1 #341745 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49799
- Type
- protein
- Length
- 205 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
- Molecule
- Regulator of G-protein signaling 4
- UniProt
- P49799
- Pockets
- 1 · best druggability 0.33
Structure
1 distinct chain · 43% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of G-protein signaling 4 | protein | 205 | 43% helix, 0% strand | P49799 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.33 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 1AGR · Complex of ALF4-activated gi-alpha-1 with RGS4 · an experimental structure of the same protein · chain A against E, TM-score 0.62
- 1AGR · Complex of ALF4-activated gi-alpha-1 with RGS4 · an experimental structure of the same protein · chain A against E, TM-score 0.62
- 1EZT · High-resolution solution structure of free RGS4 by NMR · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 1EZT · High-resolution solution structure of free RGS4 by NMR · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 1EZY · High-resolution solution structure of free RGS4 by NMR · an experimental structure of the same protein · chain A against A, TM-score 0.56
- 1EZY · High-resolution solution structure of free RGS4 by NMR · an experimental structure of the same protein · chain A against A, TM-score 0.56
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49799
- Elsewhere: UniProt P49799 · AlphaFold DB P49799
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.