MolNFT v1 · #341725 · protein
AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 22 (Q8NE09)
Q8NE09: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 22 (Q8NE09)”. 10 pockets (best druggability 0.86). MolNFT v1 #341725 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8NE09
- Type
- protein
- Length
- 1,264 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- Regulator of G-protein signaling 22
- UniProt
- Q8NE09
- Pockets
- 10 · best druggability 0.86
Structure
1 distinct chain · 47% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of G-protein signaling 22 | protein | 1264 | 47% helix, 4% strand | Q8NE09 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1176 | 0.86 | 0.87 | 103 | empty |
| 2 | 1106 | 0.81 | 0.82 | 79 | empty |
| 3 | 564 | 0.67 | 0.77 | 54 | empty |
| 4 | 239 | 0.55 | 0.78 | 32 | empty |
| 5 | 159 | 0.52 | 0.79 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NE09
- Elsewhere: UniProt Q8NE09 · AlphaFold DB Q8NE09
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