MolNFT v1 · #341711 · protein
AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 1 (Q8H1F2)
Q8H1F2: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 1 (Q8H1F2)”. 6 pockets (best druggability 0.80). MolNFT v1 #341711 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8H1F2
- Type
- protein
- Length
- 459 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC8d0a0DC57E6d8881262B3e948BBDE57dA8654E4
- Molecule
- Regulator of G-protein signaling 1
- UniProt
- Q8H1F2
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 65% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of G-protein signaling 1 | protein | 459 | 65% helix, 0% strand | Q8H1F2 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 929 | 0.80 | 0.82 | 73 | empty |
| 2 | 305 | 0.77 | 0.88 | 46 | empty |
| 3 | 89 | 0.74 | 0.96 | 22 | empty |
| 4 | 426 | 0.64 | 0.78 | 44 | empty |
| 5 | 79 | 0.33 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8H1F2
- Elsewhere: UniProt Q8H1F2 · AlphaFold DB Q8H1F2
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