MolNFT v1 · #341690 · protein
AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 12 (O08774)
O08774: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 12 (O08774)”. 7 pockets (best druggability 0.71). MolNFT v1 #341690 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O08774
- Type
- protein
- Length
- 1,387 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x45473fAA989FebC0f35D59ce60cc02F77c34828a
- Molecule
- Regulator of G-protein signaling 12
- UniProt
- O08774
- Pockets
- 7 · best druggability 0.71
Structure
1 distinct chain · 17% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of G-protein signaling 12 | protein | 1387 | 17% helix, 10% strand | O08774 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 977 | 0.71 | 0.75 | 80 | empty |
| 2 | 409 | 0.66 | 0.79 | 46 | empty |
| 3 | 300 | 0.60 | 0.78 | 34 | empty |
| 4 | 107 | 0.44 | 0.79 | 21 | empty |
| 5 | 99 | 0.35 | 0.74 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O08774
- Elsewhere: UniProt O08774 · AlphaFold DB O08774
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