MolNFT v1 · #341680 · protein
AlphaFold monomer V2.0 prediction for regulator of G-protein signaling rgs-10 (O45523)
O45523: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling rgs-10 (O45523)”. 5 pockets (best druggability 0.53). MolNFT v1 #341680 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O45523
- Type
- protein
- Length
- 270 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6227512B0B04f05c48A3f9Bb2A26C737dAb650E8
- Molecule
- Regulator of G-protein signaling rgs-10
- UniProt
- O45523
- Pockets
- 5 · best druggability 0.53
Structure
1 distinct chain · 61% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of G-protein signaling rgs-10 | protein | 270 | 61% helix, 3% strand | O45523 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 82 | 0.53 | 0.84 | 20 | empty |
| 2 | 110 | 0.51 | 0.81 | 19 | empty |
| 3 | 125 | 0.38 | 0.74 | 26 | empty |
| 4 | 66 | 0.38 | 0.78 | 13 | empty |
| 5 | 55 | 0.31 | 0.75 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O45523
- Elsewhere: UniProt O45523 · AlphaFold DB O45523
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