MolNFT v1 · #341675 · protein
AlphaFold monomer V2.0 prediction for RAS-specific guanine nucleotide-releasing factor 2 (Q99JE4)
Q99JE4: “AlphaFold monomer V2.0 prediction for RAS-specific guanine nucleotide-releasing factor 2 (Q99JE4)”. 9 pockets (best druggability 0.85). MolNFT v1 #341675 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q99JE4
- Type
- protein
- Length
- 1,190 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0DC839D07bBC2D4EB1d6fD9d3D00815fD794FED2
- Molecule
- RAS-specific guanine nucleotide-releasing factor 2
- UniProt
- Q99JE4
- Pockets
- 9 · best druggability 0.85
Structure
1 distinct chain · 53% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAS-specific guanine nucleotide-releasing factor 2 | protein | 1190 | 53% helix, 9% strand | Q99JE4 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1153 | 0.85 | 0.86 | 111 | empty |
| 2 | 234 | 0.60 | 0.80 | 28 | empty |
| 3 | 113 | 0.53 | 0.82 | 20 | empty |
| 4 | 258 | 0.50 | 0.74 | 38 | empty |
| 5 | 212 | 0.46 | 0.74 | 24 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99JE4
- Elsewhere: UniProt Q99JE4 · AlphaFold DB Q99JE4
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