MolNFT v1 · #341665 · protein
AlphaFold monomer V2.0 prediction for RAS-specific guanine nucleotide-releasing factor RALGPS1 (A2AR50)
A2AR50: “AlphaFold monomer V2.0 prediction for RAS-specific guanine nucleotide-releasing factor RALGPS1 (A2AR50)”. 5 pockets (best druggability 0.64). MolNFT v1 #341665 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A2AR50
- Type
- protein
- Length
- 585 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf23FAc8E9E29c5e2e2c0614b611FB353464fD274
- Molecule
- RAS-specific guanine nucleotide-releasing factor RALGPS1
- UniProt
- A2AR50
- Pockets
- 5 · best druggability 0.64
Structure
1 distinct chain · 35% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAS-specific guanine nucleotide-releasing factor RALGPS1 | protein | 585 | 35% helix, 9% strand | A2AR50 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 227 | 0.64 | 0.83 | 32 | empty |
| 2 | 418 | 0.62 | 0.76 | 42 | empty |
| 3 | 120 | 0.42 | 0.76 | 27 | empty |
| 4 | 54 | 0.31 | 0.76 | 12 | empty |
| 5 | 59 | 0.29 | 0.75 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2AR50
- Elsewhere: UniProt A2AR50 · AlphaFold DB A2AR50
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