MolNFT v1 · #341639 · protein
AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor subunit RGP1 (P16664)
P16664: “AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor subunit RGP1 (P16664)”. 5 pockets (best druggability 0.74). MolNFT v1 #341639 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P16664
- Type
- protein
- Length
- 663 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x71112d4fF7ebb3b617963c05f052289e073082FD
- Molecule
- Guanine nucleotide exchange factor subunit RGP1
- UniProt
- P16664
- Pockets
- 5 · best druggability 0.74
Structure
1 distinct chain · 20% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanine nucleotide exchange factor subunit RGP1 | protein | 663 | 20% helix, 32% strand | P16664 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1025 | 0.74 | 0.77 | 104 | empty |
| 2 | 311 | 0.54 | 0.75 | 28 | empty |
| 3 | 128 | 0.44 | 0.77 | 22 | empty |
| 4 | 138 | 0.43 | 0.76 | 22 | empty |
| 5 | 93 | 0.42 | 0.78 | 19 | empty |
Compared structures
- 9AYR · Structure of a Ric1-Rgp1-Rab6 activation intermediate · an experimental structure of the same protein · chain A against B, TM-score 0.60
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16664
- Elsewhere: UniProt P16664 · AlphaFold DB P16664
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