MolNFT v1 · #341496 · protein
AlphaFold monomer V2.0 prediction for RHO1 guanine nucleotide exchange factor 1 (Q9Y7U6)
Q9Y7U6: “AlphaFold monomer V2.0 prediction for RHO1 guanine nucleotide exchange factor 1 (Q9Y7U6)”. 13 pockets (best druggability 0.80). MolNFT v1 #341496 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Y7U6
- Type
- protein
- Length
- 1,334 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x661f92Fc5950020C7aB410B5F5b9a3f429F49Ae5
- Molecule
- RHO1 guanine nucleotide exchange factor 1
- UniProt
- Q9Y7U6
- Pockets
- 13 · best druggability 0.80
Structure
1 distinct chain · 22% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RHO1 guanine nucleotide exchange factor 1 | protein | 1334 | 22% helix, 19% strand | Q9Y7U6 |
Pockets
13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 693 | 0.80 | 0.84 | 60 | empty |
| 2 | 1168 | 0.75 | 0.78 | 91 | empty |
| 3 | 474 | 0.62 | 0.75 | 41 | empty |
| 4 | 440 | 0.57 | 0.74 | 43 | empty |
| 5 | 130 | 0.57 | 0.83 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y7U6
- Elsewhere: UniProt Q9Y7U6 · AlphaFold DB Q9Y7U6
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