MolNFT v1 · #341469 · protein
AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 3 (Q8GYY5)
Q8GYY5: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 3 (Q8GYY5)”. 5 pockets (best druggability 0.67). MolNFT v1 #341469 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8GYY5
- Type
- protein
- Length
- 455 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
- Molecule
- Rho GTPase-activating protein 3
- UniProt
- Q8GYY5
- Pockets
- 5 · best druggability 0.67
Structure
1 distinct chain · 37% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rho GTPase-activating protein 3 | protein | 455 | 37% helix, 3% strand | Q8GYY5 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 686 | 0.67 | 0.76 | 58 | empty |
| 2 | 127 | 0.59 | 0.84 | 28 | empty |
| 3 | 109 | 0.52 | 0.83 | 19 | empty |
| 4 | 109 | 0.37 | 0.74 | 15 | empty |
| 5 | 62 | 0.30 | 0.75 | 10 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8GYY5
- Elsewhere: UniProt Q8GYY5 · AlphaFold DB Q8GYY5
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