MolNFT v1 · #341454 · protein
AlphaFold monomer V2.0 prediction for probable rho-type GTPase- activating protein 4 (O74360)
O74360 · Probable rho-type GTPase-activating protein 4: “AlphaFold monomer V2.0 prediction for probable rho-type GTPase- activating protein 4 (O74360)”. 7 pockets (best druggability 0.63). MolNFT v1 #341454 on GenesisL1: 3D structure…
- Accession
- O74360
- Type
- protein
- Length
- 933 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4125F0397632Ff961F9e4d00d2F55Bf9b25e687
- Molecule
- Probable rho-type GTPase-activating protein 4
- UniProt
- O74360
- Pockets
- 7 · best druggability 0.63
Structure
1 distinct chain · 34% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable rho-type GTPase-activating protein 4 | protein | 933 | 34% helix, 4% strand | O74360 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 467 | 0.63 | 0.76 | 43 | empty |
| 2 | 118 | 0.59 | 0.85 | 17 | empty |
| 3 | 250 | 0.49 | 0.74 | 32 | empty |
| 4 | 96 | 0.36 | 0.75 | 21 | empty |
| 5 | 74 | 0.32 | 0.75 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74360
- Elsewhere: UniProt O74360 · AlphaFold DB O74360
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