MolNFT v1 · #341443 · protein
AlphaFold monomer V2.0 prediction for rho-type GTPase-activating protein 1 (O43052)
O43052: “AlphaFold monomer V2.0 prediction for rho-type GTPase-activating protein 1 (O43052)”. 14 pockets (best druggability 0.76). MolNFT v1 #341443 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O43052
- Type
- protein
- Length
- 1,150 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x35612D34a32C306CA4fc1edA9360D1F717e25950
- Molecule
- Rho-type GTPase-activating protein 1
- UniProt
- O43052
- Pockets
- 14 · best druggability 0.76
Structure
1 distinct chain · 38% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rho-type GTPase-activating protein 1 | protein | 1150 | 38% helix, 8% strand | O43052 |
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 980 | 0.76 | 0.78 | 65 | empty |
| 2 | 522 | 0.70 | 0.79 | 36 | empty |
| 3 | 212 | 0.56 | 0.79 | 25 | empty |
| 4 | 161 | 0.55 | 0.80 | 21 | empty |
| 5 | 330 | 0.53 | 0.74 | 40 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43052
- Elsewhere: UniProt O43052 · AlphaFold DB O43052
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