MolNFT v1 · #341248 · protein

AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase rififylin (Q8WZ73)

Q8WZ73: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase rififylin (Q8WZ73)”. 4 pockets (best druggability 0.53). MolNFT v1 #341248 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8WZ73
Type: protein
Length: 363 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x560C3688d3CACd8C45f90Cc8822C42baFa3B0548
Molecule: E3 ubiquitin-protein ligase rififylin
UniProt: Q8WZ73
Pockets: 4 · best druggability 0.53

Structure

1 distinct chain · 24% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase rififylin	protein	363	24% helix, 6% strand	Q8WZ73

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	120	0.53	0.82	19	empty
2	130	0.39	0.74	16	empty
3	105	0.35	0.73	12	empty
4	72	0.34	0.76	18	empty

Compared structures

1Y02 · Crystal Structure of a FYVE-type domain from caspase regulator CARP2 · an experimental structure of the same protein · chain A against A, TM-score 0.25
1Y02 · Crystal structure of a fyve-type domain from caspase regulator CARP2 · an experimental structure of the same protein · chain A against A, TM-score 0.25

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WZ73
Elsewhere: UniProt Q8WZ73 · AlphaFold DB Q8WZ73

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