MolNFT v1 · #341183 · protein

AlphaFold monomer V2.0 prediction for replication factor C large subunit (Q4JAB1)

Q4JAB1: “AlphaFold monomer V2.0 prediction for replication factor C large subunit (Q4JAB1)”. 4 pockets (best druggability 0.70). MolNFT v1 #341183 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q4JAB1
Type: protein
Length: 437 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
Molecule: Replication factor C large subunit
UniProt: Q4JAB1
Pockets: 4 · best druggability 0.70

Structure

1 distinct chain · 60% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Replication factor C large subunit	protein	437	60% helix, 7% strand	Q4JAB1

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	149	0.70	0.90	25	empty
2	174	0.51	0.77	30	empty
3	68	0.30	0.74	17	empty
4	56	0.28	0.74	13	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4JAB1
Elsewhere: UniProt Q4JAB1 · AlphaFold DB Q4JAB1

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