GL1X · GenesisL1 explorer

MolNFT v1 · #340713 · protein

AlphaFold monomer V2.0 prediction for peptide chain release factor 3 (B7LEM0)

B7LEM0: “AlphaFold monomer V2.0 prediction for peptide chain release factor 3 (B7LEM0)”. 3 pockets (best druggability 0.70). MolNFT v1 #340713 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
B7LEM0
Type
protein
Length
529 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x661f92Fc5950020C7aB410B5F5b9a3f429F49Ae5
Molecule
Peptide chain release factor 3
UniProt
B7LEM0
Pockets
3 · best druggability 0.70

Structure

1 distinct chain · 30% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APeptide chain release factor 3protein52930% helix, 30% strandB7LEM0

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11260.700.9123empty
26550.690.7748empty
3670.340.7714empty

Compared structures

  • 6GWT · Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and… · an experimental structure of the same protein · chain A against w, TM-score 0.89
  • 7M5D · Cryo-EM structure of a non-rotated E.coli 70S ribosome in complex with RF3-GTP, RF1 and… · an experimental structure of the same protein · chain A against 7, TM-score 0.85

Analyse

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