MolNFT v1 · #339391 · protein

AlphaFold monomer V2.0 prediction for RE1-silencing transcription factor (Q13127)

Q13127: “AlphaFold monomer V2.0 prediction for RE1-silencing transcription factor (Q13127)”. 3 pockets (best druggability 0.47). MolNFT v1 #339391 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q13127
Type: protein
Length: 1,097 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
Molecule: RE1-silencing transcription factor
UniProt: Q13127
Pockets: 3 · best druggability 0.47

Structure

1 distinct chain · 15% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RE1-silencing transcription factor	protein	1097	15% helix, 4% strand	Q13127

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	259	0.47	0.73	32	empty
2	129	0.39	0.74	22	empty
3	66	0.27	0.72	13	empty

Compared structures

2CZY · Solution structure of the NRSF/REST-mSin3B PAH1 complex · an experimental structure of the same protein · chain A against B, TM-score 0.01
2CZY · Solution structure of the NRSF/REST-MSIN3B PAH1 complex · an experimental structure of the same protein · chain A against B, TM-score 0.01

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13127
Elsewhere: UniProt Q13127 · AlphaFold DB Q13127

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