MolNFT v1 · #335510 · protein

AlphaFold monomer V2.0 prediction for caax prenyl protease 2 (Q6LZY8)

Q6LZY8: “AlphaFold monomer V2.0 prediction for caax prenyl protease 2 (Q6LZY8)”. 1 pocket (best druggability 0.76). MolNFT v1 #335510 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q6LZY8
Type: protein
Length: 271 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
Molecule: Caax prenyl protease 2
UniProt: Q6LZY8
Pockets: 1 · best druggability 0.76

Structure

1 distinct chain · 79% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Caax prenyl protease 2	protein	271	79% helix, 1% strand	Q6LZY8

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	571	0.76	0.82	39	empty

Compared structures

4CAD · Mechanism of farnesylated caax protein processing by the integral membrane protease RCE1 · an experimental structure of the same protein · chain A against I, TM-score 0.93
4CAD · Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1 · an experimental structure of the same protein · chain A against I, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6LZY8
Elsewhere: UniProt Q6LZY8 · AlphaFold DB Q6LZY8

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