MolNFT v1 · #332768 · protein
AlphaFold monomer V2.0 prediction for RAS GTPase-activating protein 3 (Q60790)
Q60790: “AlphaFold monomer V2.0 prediction for RAS GTPase-activating protein 3 (Q60790)”. 14 pockets (best druggability 0.76). MolNFT v1 #332768 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q60790
- Type
- protein
- Length
- 834 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5af3D467b030791faD852c6e2259555Bc59cf6B2
- Molecule
- RAS GTPase-activating protein 3
- UniProt
- Q60790
- Pockets
- 14 · best druggability 0.76
Structure
1 distinct chain · 37% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAS GTPase-activating protein 3 | protein | 834 | 37% helix, 25% strand | Q60790 |
Pockets
14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1093 | 0.76 | 0.78 | 89 | empty |
| 2 | 286 | 0.62 | 0.80 | 28 | empty |
| 3 | 350 | 0.62 | 0.78 | 45 | empty |
| 4 | 213 | 0.53 | 0.77 | 26 | empty |
| 5 | 205 | 0.49 | 0.75 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q60790
- Elsewhere: UniProt Q60790 · AlphaFold DB Q60790
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