MolNFT v1 · #327061 · protein
AlphaFold monomer V2.0 prediction for orotidine 5'-phosphate decarboxylase (P08244)
P08244: “AlphaFold monomer V2.0 prediction for orotidine 5'-phosphate decarboxylase (P08244)”. 2 pockets (best druggability 0.56). MolNFT v1 #327061 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P08244
- Type
- protein
- Length
- 245 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1Eec5F29CD795323506a0E09aeC21c942c4b00a7
- Molecule
- Orotidine 5'-phosphate decarboxylase
- UniProt
- P08244
- Pockets
- 2 · best druggability 0.56
Structure
1 distinct chain · 47% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Orotidine 5'-phosphate decarboxylase | protein | 245 | 47% helix, 16% strand | P08244 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 228 | 0.56 | 0.78 | 33 | empty |
| 2 | 66 | 0.30 | 0.75 | 11 | empty |
Compared structures
- 1EIX · Structure of orotidine 5'-monophosphate decarboxylase from E. COLI, co-crystallised with… · an experimental structure of the same protein · chain A against C, TM-score 0.91
- 1EIX · Structure of orotidine 5'-monophosphate decarboxylase from E. COLI, co-crystallised with… · an experimental structure of the same protein · chain A against C, TM-score 0.91
- 1JJK · Selenomethionine substitution of orotidine-5'-monophosphate decarboxylase from E. COLI… · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 1JJK · Selenomethionine Substitution of Orotidine-5'-monophosphate Decarboxylase from E. coli… · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 1L2U · Orotidine 5'-monophosphate decarboxylase from E. COLI · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 1L2U · Orotidine 5'-monophosphate decarboxylase from E. coli · an experimental structure of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08244
- Elsewhere: UniProt P08244 · AlphaFold DB P08244
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.