MolNFT v1 · #326188 · protein

AlphaFold monomer V2.0 prediction for dihydroorotate dehydrogenase (quinone) (A1TZG0)

A1TZG0: “AlphaFold monomer V2.0 prediction for dihydroorotate dehydrogenase (quinone) (A1TZG0)”. 4 pockets (best druggability 0.83). MolNFT v1 #326188 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A1TZG0
Type: protein
Length: 340 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
Molecule: Dihydroorotate dehydrogenase (quinone)
UniProt: A1TZG0
Pockets: 4 · best druggability 0.83

Structure

1 distinct chain · 46% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dihydroorotate dehydrogenase (quinone)	protein	340	46% helix, 18% strand	A1TZG0

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	201	0.83	0.97	36	empty
2	237	0.71	0.86	36	empty
3	75	0.36	0.77	19	empty
4	54	0.30	0.76	13	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A1TZG0
Elsewhere: UniProt A1TZG0 · AlphaFold DB A1TZG0

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