MolNFT v1 · #326170 · protein
AlphaFold monomer V2.0 prediction for dihydroorotate dehydrogenase (quinone) (O25655)
O25655: “AlphaFold monomer V2.0 prediction for dihydroorotate dehydrogenase (quinone) (O25655)”. 5 pockets (best druggability 0.82). MolNFT v1 #326170 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O25655
- Type
- protein
- Length
- 351 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- Dihydroorotate dehydrogenase (quinone)
- UniProt
- O25655
- Pockets
- 5 · best druggability 0.82
Structure
1 distinct chain · 47% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dihydroorotate dehydrogenase (quinone) | protein | 351 | 47% helix, 17% strand | O25655 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 188 | 0.82 | 0.97 | 41 | empty |
| 2 | 233 | 0.65 | 0.82 | 28 | empty |
| 3 | 109 | 0.47 | 0.80 | 21 | empty |
| 4 | 82 | 0.45 | 0.81 | 20 | empty |
| 5 | 50 | 0.24 | 0.72 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O25655
- Elsewhere: UniProt O25655 · AlphaFold DB O25655
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