MolNFT v1 · #325553 · protein

AlphaFold monomer V2.0 prediction for dihydroorotase (Q81WF0)

Q81WF0: “AlphaFold monomer V2.0 prediction for dihydroorotase (Q81WF0)”. 3 pockets (best druggability 0.49). MolNFT v1 #325553 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q81WF0
Type: protein
Length: 428 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
Molecule: Dihydroorotase
UniProt: Q81WF0
Pockets: 3 · best druggability 0.49

Structure

1 distinct chain · 34% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dihydroorotase	protein	428	34% helix, 22% strand	Q81WF0

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	201	0.49	0.76	31	empty
2	96	0.44	0.79	18	empty
3	54	0.26	0.73	18	empty

Compared structures

3MPG · Dihydroorotase from Bacillus anthracis · an experimental structure of the same protein · chain A against A, TM-score 0.99
3MPG · Dihydroorotase from bacillus anthracis · an experimental structure of the same protein · chain A against A, TM-score 0.99
4YIW · Dihydroorotase from bacillus anthracis with substrate bound · an experimental structure of the same protein · chain A against B, TM-score 0.99
4YIW · Dihydroorotase from bacillus anthracis with substrate bound · an experimental structure of the same protein · chain A against B, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q81WF0
Elsewhere: UniProt Q81WF0 · AlphaFold DB Q81WF0

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.