MolNFT v1 · #323437 · protein
AlphaFold monomer V2.0 prediction for 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase (Q57600)
Q57600: “AlphaFold monomer V2.0 prediction for 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl…”. 2 pockets (best druggability 0.70). MolNFT v1 #323437 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q57600
- Type
- protein
- Length
- 361 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xDC743587FCBF7fa9934EA80Fa8ee6DB1899C6b27
- Molecule
- 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase
- UniProt
- Q57600
- Pockets
- 2 · best druggability 0.70
Structure
1 distinct chain · 42% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | protein | 361 | 42% helix, 22% strand | Q57600 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 728 | 0.70 | 0.77 | 59 | empty |
| 2 | 58 | 0.32 | 0.77 | 18 | empty |
Compared structures
- 2R7K · Crystal structure of faicar synthetase (purp) from M. jannaschii complexed with amppcp… · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 2R7K · Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with AMPPCP… · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 2R7L · Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with ATP and… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 2R7L · Crystal structure of faicar synthetase (purp) from M. jannaschii complexed with ATP and… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 2R7M · Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with AMP · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 2R7M · Crystal structure of faicar synthetase (purp) from M. jannaschii complexed with AMP · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 2R7N · Crystal structure of faicar synthetase (purp) from M. jannaschii complexed with ADP and… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 2R7N · Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with ADP and… · an experimental structure of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q57600
- Elsewhere: UniProt Q57600 · AlphaFold DB Q57600
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