GL1X · GenesisL1 explorer

MolNFT v1 · #323419 · protein

AlphaFold monomer V2.0 prediction for imp cyclohydrolase (O27099)

O27099: “AlphaFold monomer V2.0 prediction for imp cyclohydrolase (O27099)”. 1 pocket (best druggability 0.46). MolNFT v1 #323419 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O27099
Type
protein
Length
202 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
Molecule
Imp cyclohydrolase
UniProt
O27099
Pockets
1 · best druggability 0.46

Structure

1 distinct chain · 22% helix, 39% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AImp cyclohydrolaseprotein20222% helix, 39% strandO27099

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1800.460.8117empty

Compared structures

  • 2NTL · Crystal structure of PurO/AICAR from Methanothermobacter thermoautotrophicus · an experimental structure of the same protein · chain A against C, TM-score 1.00
  • 2NTL · Crystal structure of PURO/AICAR from methanothermobacter thermoautotrophicus · an experimental structure of the same protein · chain A against C, TM-score 1.00
  • 2NTK · Crystal structure of PURO/IMP from methanothermobacter thermoautotrophicus · an experimental structure of the same protein · chain A against B, TM-score 0.99
  • 2NTK · Crystal structure of PurO/IMP from Methanothermobacter thermoautotrophicus · an experimental structure of the same protein · chain A against B, TM-score 0.99
  • 2NTM · Crystal structure of PurO from Methanothermobacter thermoautotrophicus · an experimental structure of the same protein · chain A against D, TM-score 0.99
  • 2NTM · Crystal structure of puro from methanothermobacter thermoautotrophicus · an experimental structure of the same protein · chain A against D, TM-score 0.99
  • 1KUU · Crystal structure of methanobacterium thermoautotrophicum conserved protein MTH1020… · an experimental structure of the same protein · chain A against A, TM-score 0.99
  • 1KUU · Crystal structure of methanobacterium thermoautotrophicum conserved protein MTH1020… · an experimental structure of the same protein · chain A against A, TM-score 0.99

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