MolNFT v1 · #320634 · protein
AlphaFold monomer V2.0 prediction for probable phosphoribosylformylglycinamidine synthase (O14228)
O14228: “AlphaFold monomer V2.0 prediction for probable phosphoribosylformylglycinamidine synthase (O14228)”. 11 pockets (best druggability 0.86). MolNFT v1 #320634 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O14228
- Type
- protein
- Length
- 1,323 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
- Molecule
- Probable phosphoribosylformylglycinamidine synthase
- UniProt
- O14228
- Pockets
- 11 · best druggability 0.86
Structure
1 distinct chain · 33% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable phosphoribosylformylglycinamidine synthase | protein | 1323 | 33% helix, 26% strand | O14228 |
Pockets
11 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 300 | 0.86 | 0.97 | 40 | empty |
| 2 | 172 | 0.82 | 0.97 | 30 | empty |
| 3 | 926 | 0.81 | 0.83 | 100 | empty |
| 4 | 546 | 0.76 | 0.83 | 66 | empty |
| 5 | 303 | 0.72 | 0.85 | 52 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14228
- Elsewhere: UniProt O14228 · AlphaFold DB O14228
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