MolNFT v1 · #320327 · protein

AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (P0A539)

P0A539: “AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (P0A539)”. 2 pockets (best druggability 0.68). MolNFT v1 #320327 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P0A539
Type: protein
Length: 268 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x1ED4a68B4011314730adE976b56Ad4cA21b54dcD
Molecule: Purine nucleoside phosphorylase
UniProt: P0A539
Pockets: 2 · best druggability 0.68

Structure

1 distinct chain · 34% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Purine nucleoside phosphorylase	protein	268	34% helix, 23% strand	P0A539

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	131	0.68	0.90	27	empty
2	111	0.36	0.74	24	empty

Compared structures

3IX2 · Crystal structure of purine nucleoside phosphorylase from mycobacterium tuberculosis in… · an experimental structure of the same protein · chain A against A, TM-score 0.94
3IX2 · Crystal structure of purine nucleoside phosphorylase from mycobacterium tuberculosis in… · an experimental structure of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A539
Elsewhere: UniProt P0A539 · AlphaFold DB P0A539

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