MolNFT v1 · #319885 · protein
AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase V (P70289)
P70289: “AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase V (P70289)”. 14 pockets (best druggability 0.67). MolNFT v1 #319885 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P70289
- Type
- protein
- Length
- 1,705 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- Receptor-type tyrosine-protein phosphatase V
- UniProt
- P70289
- Pockets
- 14 · best druggability 0.67
Structure
1 distinct chain · 15% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Receptor-type tyrosine-protein phosphatase V | protein | 1705 | 15% helix, 40% strand | P70289 |
Pockets
14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 792 | 0.67 | 0.75 | 76 | empty |
| 2 | 452 | 0.59 | 0.75 | 45 | empty |
| 3 | 59 | 0.53 | 0.88 | 22 | empty |
| 4 | 192 | 0.51 | 0.77 | 36 | empty |
| 5 | 276 | 0.50 | 0.73 | 40 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P70289
- Elsewhere: UniProt P70289 · AlphaFold DB P70289
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