MolNFT v1 · #319884 · protein
AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase U (B1AUH1)
B1AUH1: “AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase U (B1AUH1)”. 12 pockets (best druggability 0.77). MolNFT v1 #319884 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B1AUH1
- Type
- protein
- Length
- 1,446 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
- Molecule
- Receptor-type tyrosine-protein phosphatase U
- UniProt
- B1AUH1
- Pockets
- 12 · best druggability 0.77
Structure
1 distinct chain · 19% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Receptor-type tyrosine-protein phosphatase U | protein | 1446 | 19% helix, 32% strand | B1AUH1 |
Pockets
12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 912 | 0.77 | 0.80 | 94 | empty |
| 2 | 890 | 0.71 | 0.76 | 71 | empty |
| 3 | 1032 | 0.71 | 0.75 | 81 | empty |
| 4 | 271 | 0.58 | 0.78 | 27 | empty |
| 5 | 161 | 0.56 | 0.81 | 28 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B1AUH1
- Elsewhere: UniProt B1AUH1 · AlphaFold DB B1AUH1
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