MolNFT v1 · #319881 · protein
AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase U (Q6YI48)
Q6YI48: “AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase U (Q6YI48)”. 11 pockets (best druggability 0.85). MolNFT v1 #319881 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6YI48
- Type
- protein
- Length
- 1,434 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
- Molecule
- Receptor-type tyrosine-protein phosphatase U
- UniProt
- Q6YI48
- Pockets
- 11 · best druggability 0.85
Structure
1 distinct chain · 19% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Receptor-type tyrosine-protein phosphatase U | protein | 1434 | 19% helix, 32% strand | Q6YI48 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1003 | 0.85 | 0.86 | 93 | empty |
| 2 | 756 | 0.75 | 0.80 | 66 | empty |
| 3 | 441 | 0.68 | 0.80 | 44 | empty |
| 4 | 100 | 0.51 | 0.82 | 22 | empty |
| 5 | 112 | 0.47 | 0.79 | 17 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6YI48
- Elsewhere: UniProt Q6YI48 · AlphaFold DB Q6YI48
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