MolNFT v1 · #319740 · protein
AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase 99A (P35832)
P35832: “AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase 99A (P35832)”. 11 pockets (best druggability 0.75). MolNFT v1 #319740 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P35832
- Type
- protein
- Length
- 1,301 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbDA05C32aD6eE153C8C5A78dfa48d7Ba25694fea
- Molecule
- Tyrosine-protein phosphatase 99A
- UniProt
- P35832
- Pockets
- 11 · best druggability 0.75
Structure
1 distinct chain · 26% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein phosphatase 99A | protein | 1301 | 26% helix, 19% strand | P35832 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1195 | 0.75 | 0.78 | 98 | empty |
| 2 | 887 | 0.73 | 0.77 | 72 | empty |
| 3 | 421 | 0.62 | 0.76 | 48 | empty |
| 4 | 102 | 0.56 | 0.84 | 16 | empty |
| 5 | 350 | 0.55 | 0.74 | 37 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35832
- Elsewhere: UniProt P35832 · AlphaFold DB P35832
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