MolNFT v1 · #319736 · protein
AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase 69D (P16620)
P16620: “AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase 69D (P16620)”. 12 pockets (best druggability 0.75). MolNFT v1 #319736 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P16620
- Type
- protein
- Length
- 1,462 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa39B2015befF3243019A855540D161D74D3E92C6
- Molecule
- Tyrosine-protein phosphatase 69D
- UniProt
- P16620
- Pockets
- 12 · best druggability 0.75
Structure
1 distinct chain · 22% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein phosphatase 69D | protein | 1462 | 22% helix, 32% strand | P16620 |
Pockets
12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 113 | 0.75 | 0.95 | 28 | empty |
| 2 | 187 | 0.67 | 0.86 | 29 | empty |
| 3 | 324 | 0.58 | 0.77 | 35 | empty |
| 4 | 81 | 0.45 | 0.81 | 16 | empty |
| 5 | 126 | 0.42 | 0.76 | 18 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16620
- Elsewhere: UniProt P16620 · AlphaFold DB P16620
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