MolNFT v1 · #319731 · protein
AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase 4 (P28192)
P28192: “AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase 4 (P28192)”. 9 pockets (best druggability 0.70). MolNFT v1 #319731 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P28192
- Type
- protein
- Length
- 1,159 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x42fB943ABB54FcE752274CE38bcF736f69B067D1
- Molecule
- Tyrosine-protein phosphatase 4
- UniProt
- P28192
- Pockets
- 9 · best druggability 0.70
Structure
1 distinct chain · 21% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein phosphatase 4 | protein | 1159 | 21% helix, 31% strand | P28192 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 720 | 0.70 | 0.77 | 64 | empty |
| 2 | 52 | 0.54 | 0.89 | 22 | empty |
| 3 | 275 | 0.53 | 0.75 | 28 | empty |
| 4 | 261 | 0.50 | 0.74 | 26 | empty |
| 5 | 114 | 0.48 | 0.80 | 24 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P28192
- Elsewhere: UniProt P28192 · AlphaFold DB P28192
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