MolNFT v1 · #319719 · protein

AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type ptp-2 (G5EC24)

G5EC24: “AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type ptp-2 (G5EC24)”. 8 pockets (best druggability 0.74). MolNFT v1 #319719 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: G5EC24
Type: protein
Length: 668 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
Molecule: Tyrosine-protein phosphatase non-receptor type ptp-2
UniProt: G5EC24
Pockets: 8 · best druggability 0.74

Structure

1 distinct chain · 28% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tyrosine-protein phosphatase non-receptor type ptp-2	protein	668	28% helix, 20% strand	G5EC24

Pockets

8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	936	0.74	0.77	82	empty
2	524	0.66	0.77	43	empty
3	104	0.59	0.86	24	empty
4	53	0.59	0.91	19	empty
5	251	0.58	0.78	36	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G5EC24
Elsewhere: UniProt G5EC24 · AlphaFold DB G5EC24

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