MolNFT v1 · #319652 · protein

AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type 3 (A2ALK8)

A2ALK8: “AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type 3 (A2ALK8)”. 8 pockets (best druggability 0.77). MolNFT v1 #319652 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A2ALK8
Type: protein
Length: 913 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
Molecule: Tyrosine-protein phosphatase non-receptor type 3
UniProt: A2ALK8
Pockets: 8 · best druggability 0.77

Structure

1 distinct chain · 24% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tyrosine-protein phosphatase non-receptor type 3	protein	913	24% helix, 20% strand	A2ALK8

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	831	0.77	0.81	83	empty
2	416	0.67	0.80	54	empty
3	370	0.58	0.76	46	empty
4	152	0.49	0.77	24	empty
5	98	0.41	0.77	16	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A2ALK8
Elsewhere: UniProt A2ALK8 · AlphaFold DB A2ALK8

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