MolNFT v1 · #319642 · protein

AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type 23 (Q6PB44)

Q6PB44: “AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type 23 (Q6PB44)”. 12 pockets (best druggability 0.71). MolNFT v1 #319642 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q6PB44
Type: protein
Length: 1,692 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
Molecule: Tyrosine-protein phosphatase non-receptor type 23
UniProt: Q6PB44
Pockets: 12 · best druggability 0.71

Structure

1 distinct chain · 41% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tyrosine-protein phosphatase non-receptor type 23	protein	1692	41% helix, 4% strand	Q6PB44

Pockets

12 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	939	0.71	0.76	82	empty
2	269	0.53	0.75	33	empty
3	235	0.50	0.75	24	empty
4	229	0.50	0.75	26	empty
5	215	0.46	0.74	27	empty

Compared structures

2W10 · Mona SH3C in complex · an experimental structure of the same protein · chain A against D, TM-score 0.01
2W10 · Mona SH3C in complex · an experimental structure of the same protein · chain A against D, TM-score 0.01

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6PB44
Elsewhere: UniProt Q6PB44 · AlphaFold DB Q6PB44

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