MolNFT v1 · #319452 · protein
AlphaFold monomer V2.0 prediction for tyrosine-protein kinase-like otk (B4HNW4)
B4HNW4: “AlphaFold monomer V2.0 prediction for tyrosine-protein kinase-like otk (B4HNW4)”. 12 pockets (best druggability 0.76). MolNFT v1 #319452 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B4HNW4
- Type
- protein
- Length
- 1,029 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x609Fa0b31fD3638CAd281535556e05E61e7eC0f8
- Molecule
- Tyrosine-protein kinase-like otk
- UniProt
- B4HNW4
- Pockets
- 12 · best druggability 0.76
Structure
1 distinct chain · 21% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase-like otk | protein | 1029 | 21% helix, 31% strand | B4HNW4 |
Pockets
12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 470 | 0.76 | 0.84 | 57 | empty |
| 2 | 328 | 0.70 | 0.83 | 32 | empty |
| 3 | 255 | 0.66 | 0.83 | 30 | empty |
| 4 | 109 | 0.56 | 0.85 | 16 | empty |
| 5 | 243 | 0.53 | 0.76 | 23 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4HNW4
- Elsewhere: UniProt B4HNW4 · AlphaFold DB B4HNW4
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