MolNFT v1 · #319448 · protein

AlphaFold monomer V2.0 prediction for tyrosine-protein kinase-like otk (Q6AWJ9)

Q6AWJ9: “AlphaFold monomer V2.0 prediction for tyrosine-protein kinase-like otk (Q6AWJ9)”. 7 pockets (best druggability 0.72). MolNFT v1 #319448 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q6AWJ9
Type: protein
Length: 1,033 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
Molecule: Tyrosine-protein kinase-like otk
UniProt: Q6AWJ9
Pockets: 7 · best druggability 0.72

Structure

1 distinct chain · 19% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tyrosine-protein kinase-like otk	protein	1033	19% helix, 30% strand	Q6AWJ9

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1134	0.72	0.76	103	empty
2	763	0.67	0.75	65	empty
3	392	0.66	0.79	42	empty
4	442	0.62	0.76	40	empty
5	83	0.36	0.76	16	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

6S9F · Drosophila otk, extracellular domains 3-5 · an experimental structure of the same protein · chain A against A, TM-score 0.26
6S9F · Drosophila OTK, extracellular domains 3-5 · an experimental structure of the same protein · chain A against A, TM-score 0.26

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6AWJ9
Elsewhere: UniProt Q6AWJ9 · AlphaFold DB Q6AWJ9

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