MolNFT v1 · #318562 · protein
AlphaFold monomer V2.0 prediction for parathyroid HORMONE/PARATHYROID hormone-related peptide receptor (P25961)
P25961: “AlphaFold monomer V2.0 prediction for parathyroid HORMONE/PARATHYROID hormone-related peptide receptor…”. 5 pockets (best druggability 0.77). MolNFT v1 #318562 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P25961
- Type
- protein
- Length
- 591 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC37B6D6A825332EfD80E4d0477aAa04293f63Ca4
- Molecule
- Parathyroid HORMONE/PARATHYROID hormone-related peptide receptor
- UniProt
- P25961
- Pockets
- 5 · best druggability 0.77
Structure
1 distinct chain · 53% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Parathyroid HORMONE/PARATHYROID hormone-related peptide receptor | protein | 591 | 53% helix, 4% strand | P25961 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 975 | 0.77 | 0.79 | 57 | empty |
| 2 | 498 | 0.70 | 0.80 | 40 | empty |
| 3 | 125 | 0.38 | 0.73 | 17 | empty |
| 4 | 117 | 0.36 | 0.73 | 14 | empty |
| 5 | 69 | 0.28 | 0.73 | 18 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25961
- Elsewhere: UniProt P25961 · AlphaFold DB P25961
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