MolNFT v1 · #318380 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase pten (Q9PUT6)
Q9PUT6: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and…”. 7 pockets (best druggability 0.78). MolNFT v1 #318380 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9PUT6
- Type
- protein
- Length
- 402 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7746095A33F2b1CD4a2D513b839bb4B33c352C5C
- Molecule
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein…
- UniProt
- Q9PUT6
- Pockets
- 7 · best druggability 0.78
Structure
1 distinct chain · 26% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase pten | protein | 402 | 26% helix, 28% strand | Q9PUT6 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 614 | 0.78 | 0.84 | 65 | empty |
| 2 | 107 | 0.54 | 0.83 | 22 | empty |
| 3 | 163 | 0.48 | 0.77 | 30 | empty |
| 4 | 69 | 0.43 | 0.81 | 14 | empty |
| 5 | 69 | 0.39 | 0.79 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9PUT6
- Elsewhere: UniProt Q9PUT6 · AlphaFold DB Q9PUT6
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