MolNFT v1 · #318376 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase pten (Q8T9S7)
Q8T9S7: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and…”. 5 pockets (best druggability 0.70). MolNFT v1 #318376 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8T9S7
- Type
- protein
- Length
- 533 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9F605311B7e26e76340423EfAfbE5e2EFc7A0b7C
- Molecule
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein…
- UniProt
- Q8T9S7
- Pockets
- 5 · best druggability 0.70
Structure
1 distinct chain · 19% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase pten | protein | 533 | 19% helix, 20% strand | Q8T9S7 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 655 | 0.70 | 0.78 | 59 | empty |
| 2 | 276 | 0.55 | 0.76 | 30 | empty |
| 3 | 147 | 0.44 | 0.76 | 24 | empty |
| 4 | 68 | 0.39 | 0.79 | 13 | empty |
| 5 | 55 | 0.26 | 0.73 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8T9S7
- Elsewhere: UniProt Q8T9S7 · AlphaFold DB Q8T9S7
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