MolNFT v1 · #318374 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 (G5EE01)
G5EE01: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and…”. 16 pockets (best druggability 0.82). MolNFT v1 #318374 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- G5EE01
- Type
- protein
- Length
- 962 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
- Molecule
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein…
- UniProt
- G5EE01
- Pockets
- 16 · best druggability 0.82
Structure
1 distinct chain · 36% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 | protein | 962 | 36% helix, 14% strand | G5EE01 |
Pockets
16 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 537 | 0.82 | 0.88 | 79 | empty |
| 2 | 404 | 0.81 | 0.89 | 39 | empty |
| 3 | 700 | 0.71 | 0.78 | 58 | empty |
| 4 | 171 | 0.65 | 0.85 | 29 | empty |
| 5 | 128 | 0.62 | 0.86 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G5EE01
- Elsewhere: UniProt G5EE01 · AlphaFold DB G5EE01
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.