MolNFT v1 · #318373 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1 (Q9FLZ5)
Q9FLZ5: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and…”. 4 pockets (best druggability 0.59). MolNFT v1 #318373 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9FLZ5
- Type
- protein
- Length
- 412 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x754211C7Fae7D5307c457b846C626ab75786652A
- Molecule
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase…
- UniProt
- Q9FLZ5
- Pockets
- 4 · best druggability 0.59
Structure
1 distinct chain · 28% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1 | protein | 412 | 28% helix, 32% strand | Q9FLZ5 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 253 | 0.59 | 0.79 | 30 | empty |
| 2 | 120 | 0.53 | 0.82 | 24 | empty |
| 3 | 111 | 0.49 | 0.81 | 20 | empty |
| 4 | 55 | 0.32 | 0.77 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9FLZ5
- Elsewhere: UniProt Q9FLZ5 · AlphaFold DB Q9FLZ5
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