MolNFT v1 · #318304 · protein
AlphaFold monomer V2.0 prediction for protein patched homolog 2 (O35595)
O35595: “AlphaFold monomer V2.0 prediction for protein patched homolog 2 (O35595)”. 14 pockets (best druggability 0.88). MolNFT v1 #318304 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O35595
- Type
- protein
- Length
- 1,182 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb0C4A94B80C0c8A38C5aE5637b6663aC73C048F3
- Molecule
- Protein patched homolog 2
- UniProt
- O35595
- Pockets
- 14 · best druggability 0.88
Structure
1 distinct chain · 50% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein patched homolog 2 | protein | 1182 | 50% helix, 7% strand | O35595 |
Pockets
14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 971 | 0.88 | 0.89 | 106 | empty |
| 2 | 185 | 0.78 | 0.92 | 28 | empty |
| 3 | 291 | 0.74 | 0.86 | 36 | empty |
| 4 | 265 | 0.64 | 0.81 | 31 | empty |
| 5 | 80 | 0.48 | 0.82 | 21 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35595
- Elsewhere: UniProt O35595 · AlphaFold DB O35595
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