MolNFT v1 · #318159 · protein

AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-protein phosphotransferase (P23533)

P23533: “AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-protein phosphotransferase (P23533)”. 3 pockets (best druggability 0.70). MolNFT v1 #318159 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P23533
Type: protein
Length: 573 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
Molecule: Phosphoenolpyruvate-protein phosphotransferase
UniProt: P23533
Pockets: 3 · best druggability 0.70

Structure

1 distinct chain · 52% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphoenolpyruvate-protein phosphotransferase	protein	573	52% helix, 15% strand	P23533

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	687	0.70	0.78	83	empty
2	831	0.70	0.76	77	empty
3	53	0.31	0.76	11	empty

Compared structures

2HRO · Structure of the full-lenght enzyme I of the pts system from staphylococcus carnosus · an experimental structure of the same protein · chain A against A, TM-score 0.61
2HRO · Structure of the full-lenght Enzyme I of the PTS system from Staphylococcus carnosus · an experimental structure of the same protein · chain A against A, TM-score 0.61

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23533
Elsewhere: UniProt P23533 · AlphaFold DB P23533

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