MolNFT v1 · #317202 · protein
AlphaFold monomer V2.0 prediction for presenilin-2 (O88777)
O88777: “AlphaFold monomer V2.0 prediction for presenilin-2 (O88777)”. 4 pockets (best druggability 0.80). MolNFT v1 #317202 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O88777
- Type
- protein
- Length
- 448 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x35612D34a32C306CA4fc1edA9360D1F717e25950
- Molecule
- Presenilin-2
- UniProt
- O88777
- Pockets
- 4 · best druggability 0.80
Structure
1 distinct chain · 54% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Presenilin-2 | protein | 448 | 54% helix, 1% strand | O88777 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1100 | 0.80 | 0.81 | 71 | empty |
| 2 | 154 | 0.56 | 0.82 | 25 | empty |
| 3 | 123 | 0.54 | 0.82 | 19 | empty |
| 4 | 75 | 0.39 | 0.77 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88777
- Elsewhere: UniProt O88777 · AlphaFold DB O88777
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