MolNFT v1 · #317198 · protein
AlphaFold monomer V2.0 prediction for presenilin-2 (P79801)
P79801: “AlphaFold monomer V2.0 prediction for presenilin-2 (P79801)”. 5 pockets (best druggability 0.80). MolNFT v1 #317198 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P79801
- Type
- protein
- Length
- 445 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
- Molecule
- Presenilin-2
- UniProt
- P79801
- Pockets
- 5 · best druggability 0.80
Structure
1 distinct chain · 56% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Presenilin-2 | protein | 445 | 56% helix, 1% strand | P79801 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1117 | 0.80 | 0.81 | 74 | empty |
| 2 | 213 | 0.58 | 0.80 | 28 | empty |
| 3 | 173 | 0.57 | 0.82 | 25 | empty |
| 4 | 60 | 0.32 | 0.75 | 13 | empty |
| 5 | 50 | 0.28 | 0.74 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P79801
- Elsewhere: UniProt P79801 · AlphaFold DB P79801
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