MolNFT v1 · #317195 · protein
AlphaFold monomer V2.0 prediction for presenilin-2 (Q9XT96)
Q9XT96: “AlphaFold monomer V2.0 prediction for presenilin-2 (Q9XT96)”. 4 pockets (best druggability 0.80). MolNFT v1 #317195 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9XT96
- Type
- protein
- Length
- 449 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3a312d9A90f3bb89BFC42BF4b95c23D7295582F9
- Molecule
- Presenilin-2
- UniProt
- Q9XT96
- Pockets
- 4 · best druggability 0.80
Structure
1 distinct chain · 56% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Presenilin-2 | protein | 449 | 56% helix, 1% strand | Q9XT96 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1084 | 0.80 | 0.81 | 68 | empty |
| 2 | 205 | 0.59 | 0.80 | 27 | empty |
| 3 | 166 | 0.57 | 0.82 | 25 | empty |
| 4 | 68 | 0.27 | 0.72 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9XT96
- Elsewhere: UniProt Q9XT96 · AlphaFold DB Q9XT96
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