MolNFT v1 · #317194 · protein
AlphaFold monomer V2.0 prediction for presenilin-1 (O12976)
O12976: “AlphaFold monomer V2.0 prediction for presenilin-1 (O12976)”. 2 pockets (best druggability 0.82). MolNFT v1 #317194 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O12976
- Type
- protein
- Length
- 433 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- Presenilin-1
- UniProt
- O12976
- Pockets
- 2 · best druggability 0.82
Structure
1 distinct chain · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Presenilin-1 | protein | 433 | 66% helix, 1% strand | O12976 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1066 | 0.82 | 0.83 | 84 | empty |
| 2 | 60 | 0.32 | 0.76 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O12976
- Elsewhere: UniProt O12976 · AlphaFold DB O12976
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