MolNFT v1 · #317187 · protein

AlphaFold monomer V2.0 prediction for presenilin-1 (Q9W6T7)

Q9W6T7: “AlphaFold monomer V2.0 prediction for presenilin-1 (Q9W6T7)”. 4 pockets (best druggability 0.80). MolNFT v1 #317187 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9W6T7
Type: protein
Length: 456 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xB35df660264f41795De49C83276C108A4ba91ADE
Molecule: Presenilin-1
UniProt: Q9W6T7
Pockets: 4 · best druggability 0.80

Structure

1 distinct chain · 60% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Presenilin-1	protein	456	60% helix, 1% strand	Q9W6T7

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1068	0.80	0.81	65	empty
2	169	0.62	0.84	24	empty
3	297	0.58	0.77	35	empty
4	71	0.30	0.74	10	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9W6T7
Elsewhere: UniProt Q9W6T7 · AlphaFold DB Q9W6T7

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