MolNFT v1 · #317069 · protein
AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 1 (O88761)
O88761: “AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 1 (O88761)”. 11 pockets (best druggability 0.85). MolNFT v1 #317069 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O88761
- Type
- protein
- Length
- 953 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
- Molecule
- 26S proteasome non-ATPase regulatory subunit 1
- UniProt
- O88761
- Pockets
- 11 · best druggability 0.85
Structure
1 distinct chain · 60% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 26S proteasome non-ATPase regulatory subunit 1 | protein | 953 | 60% helix, 4% strand | O88761 |
Pockets
11 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 951 | 0.85 | 0.87 | 106 | empty |
| 2 | 185 | 0.55 | 0.80 | 34 | empty |
| 3 | 115 | 0.40 | 0.75 | 23 | empty |
| 4 | 124 | 0.38 | 0.74 | 21 | empty |
| 5 | 72 | 0.36 | 0.77 | 20 | empty |
Compared structures
- 6EPF · Ground state 26S proteasome (GS1) · an experimental structure of the same protein · chain A against N, TM-score 0.84
- 6EPC · Ground state 26S proteasome (GS2) · an experimental structure of the same protein · chain A against N, TM-score 0.84
- 6EPE · Substrate processing state 26S proteasome (SPS2) · an experimental structure of the same protein · chain A against N, TM-score 0.84
- 6EPD · Substrate processing state 26S proteasome (SPS1) · an experimental structure of the same protein · chain A against N, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88761
- Elsewhere: UniProt O88761 · AlphaFold DB O88761
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